The sixth edition of the Paris-Saclay Junior Conference on Data Science and Engineering (JDSE) is addressed to first-year Ph.D. students, M2 students, and third-year students at Engineering schools at Paris-Saclay and Institut Polytechnique de Paris. It will offer these students the opportunity to present the scientific work developed during their internships or the first year of their Ph.D. thesis. Also, it will allow them to exchange ideas and discuss ongoing research with prestigious invited speakers, academics, and industry scientists, as well as their peers.